About 12.15pm on Saturday, emergency services rushed to Holbrook Road, near Paper Forest Road, at Mangoplah after reports a vehicle had crashed.

Police said it is believed the driver of the Mitsubishi Triton was travelling north when the vehicle left the road and hit a tree.

The driver, a 28-year-old man, was treated at the scene for non-life-threatening injuries and taken to Wagga Base Hospital.

The man's passenger, a six-year-old boy, died at the scene.

Inspector David Vine from NSW Ambulance said it was a difficult scene for first responders, as well as for the passers-by who tried to help while waiting for paramedics and police.

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"It was a truly shattering scene for the bystanders and first responders on scene," Inspector Vine said.

"I want to thank the bystanders that rendered assistance before emergency services arrived on scene, it was a very courageous act.

"Our hearts go out to the family and friends of the victim following this devastating loss of life."

A Murrumbidgee Local Health District spokesperson confirmed the man remained in a stable condition in hospital on Sunday afternoon.

Wagga mayor Greg Conkey said the fatality was a tragedy for the region and his thoughts also went out to the family and friends of the boy.

NSW Police have confirmed the driver and the boy were from Lavington.

Investigators are trying to piece together the moments leading up to the tragic crash and are calling for help from the public.

The crash scene was examined by specialist police attached to the NSW Police Southern Region Crash Investigation Unit.

As investigations continue, police are urging anyone who may have seen the vehicle prior to the crash - or who may have dashcam or CCTV footage from the area - to call Crime Stoppers on 1800 333 000.

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