About 8:45am four ambulances and the Toll ambulance rescue helicopter were dispatched to a property on Mona Vale Road at Ladysmith.

They found a man, believed to be in his 50s, with a puncture wound to his lower leg and injuries to his head, chest and abdomen.

The man was treated at the scene and then transported to Wagga Base Hospital in a serious but stable condition, according to a NSW Ambulance spokesperson.

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NSW Ambulance Southern Zone Inspector Peter Thompson said the buffalo appeared to have charged the man, knocking him over, and then gored a hole in his leg.

"The patient was in a lot of pain, so paramedics and the aeromedical team worked to control bleeding, managed his pain and stabilised him for transport," he said.

"It's a reminder of the damage a big, powerful animal like this can do to you, if it has a mind to."

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