The man, aged in his 60s, who lives in the Wagga local government area, was being treated at the city's base hospital.

The now-negative result means the number of positives cases for COVID-19 in the Murrumbidgee Local Health District stands at 45, with 10 of them in the Wagga area, as of Monday morning.

Thirty-nine of those 45 cases are considered to be recovered patients. Currently there is no one being treated for COVID-19 in any of the region's hospitals.

In total, 3526 people have been tested for COVID-19 in the MLHD.

Murrumbidgee Local Health District's director of public health Tracey Oakman told a press conference on Monday that situation had not occurred often in this region.

"It hasn't happened much at all in our area; around the state it has happened on a number of occasions, it's routine to retest those cases," she said.

"The laboratory gave indication to us that it was a low positive, so we were then able to trigger repeat testing.

"We've not been concerned about any other test that we've received to date."

Mrs Oakman said a fever had led to the man being tested for COVID-19.

"In pathology there's always cut-off areas when you're doing tests and there's different elements of what the laboratories test for," she said.

"I understand in this case the person was close to the low cut-off negative area."

Anyone who believes they may have contracted the COVID-19 virus should call the Murrumbidgee COVID-19 hotline on 1800 831 099 - daily between from 7am and 9pm - for a confidential over the phone assessment.