Health Minister Greg Hunt said an approach to market would be launched within the next 10 days for companies to put their hand up to locally produce mRNA vaccines.

He expects at least one to be made in Australia by next year.

"I won't make a guarantee on that, but I am confident that over the future period we will have mRNA production in Australia," Mr Hunt told reporters in Canberra on Thursday.

Health Department boss Brendan Murphy said the vaccine production could be broader than COVID-19, possibly extending to flu jabs.

Mr Hunt also confirmed 25 million doses of the Moderna vaccine from the United States have been secured.

The first 10 million are due to arrive this year while the rest are slated to be delivered next year.

The minister said the two-dose Moderna jabs were central to the government's plan to deal with coronavirus variants.

"Moderna is, on the advice that we have, the most advanced of the vaccine products with relation to the capacity to adapt to booster or variant requirements," Mr Hunt said.

"We don't know everything that is going to occur in this pandemic, but our goal has been to prepare for everything that is possible."

The Moderna jab has not yet been approved by the Therapeutic Goods Administration but the company is expected to apply for that soon.

People under 50 are set to receive the Moderna vaccine.

The Morrison government has again been urged to provide clarity on when it predicts the vaccine rollout will be completed, after senior ministers provided different views.

Mr Hunt said the budget's assumption was based on vaccines being available this year.

"That means we want Australians to be able to have that access to a vaccine shot over the course of the year."

The government continues to face pressure from the business community and doctors to lay out a plan for Australia's reopening, as cases dwindle and the vaccine is rolled out.

Treasurer Josh Frydenberg told reporters earlier this week all Australians who wanted to be vaccinated should have received their second dose by the end of the year, but Prime Minister Scott Morrison has walked that back.

Mr Morrison said the Treasury's budget assumptions were exactly that - assumptions and not a policy setting.

Labor frontbencher Jim Chalmers said clarity was vital.

"We cannot have a first-rate economic recovery with a third-rate vaccine rollout - we need clarity from the government about how they are going to do it."

Australian Associated Press