NSW Premier Gladys Berejiklian announced on Saturday that Wagga Base Hospital will be one of five "major vaccination hubs" that will serve 99 "regional satellite sites" that will open between March 15 and April.

Wagga was first identified as a vaccine hub location in late January and the city's aged care residents started receiving their jabs on Friday under the federal government's rollout program.

The Premier's statement said thee vaccination hubs and satellite sites will initially focus on frontline healthcare and border workers, and will eventually be followed by a wider rollout of the vaccine to the general public through the GP network.

The vaccine will be dispatched from the hubs to the satellite sites.

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Ms Berejiklian said it had been great to see the enormous enthusiasm from those receiving and giving the jabs.

"NSW is on track to achieve its goal of more than 35,000 vaccinations in the first three weeks with thousands of frontline workers already receiving their first doses thanks to excellent work of our NSW Health staff in the three initial hubs," Ms Berejiklian said.

Deputy Premier John Barilaro said it's fantastic the rollout of the vaccine will be expanded into regional NSW, including a major hub at Wagga.

"Regional NSW has endured a myriad of impacts from COVID-19 and with the vaccine now on its way, we will have the confidence and assurance we need to live fully and remain open for business," Mr Barilaro said.

Wagga vaccine hub spoke 'satellite sites'

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