Former Wagga man Patrick Gribble, who was one of just four passengers disembarking from Melbourne, was scrambling to organise logistics for his Wagga car wholesaling business.

"[There's] transport and logistic pressure, yes. I've got cars here that have been sold into Melbourne," he said at the station.

"I've got to get them to the other side, otherwise it could be shut down for a month or two and that's no good."

By the time the border closes at midnight he will have made two trips back and forth in just 24 hours - both times undergoing NSW and Victorian health authorities' preventative screening procedures. "It was interesting," he said of being screened yesterday.

"It was almost like being on Train to Busan or some sort of zombie movie. I don't think I'm terribly comfortable with people wanting my details and screening me for health checks.

"But I know the staff all pretty well there, I've travelled hundreds of times. They're always good."

Wagga railway station was quiet on what would usually have been a bustling Monday afternoon, with most people there to travel to Sydney.

Jaidyn Whitton was another passenger at the station, preparing to board the train for Melbourne.

Mr Whitton said he wasn't nervous about returning despite the second outbreak in his home city.

"I don't live in Wagga, I've just been visiting ... my mum lives down there," he said.