The Riverina will experience twice as many hot days and 28 per cent less rainfall by the year 2050, according to a study by the Australian Conservation Foundation and the Australian National University.
The study predicted that climate change will result in the Wagga ceasing to experience a traditional winter with average maximum temperatures increasing by more than four degrees.
Charles Sturt University Institute for Land, Water and Society's Dr Jonathon Howard said the report was "spot on" in its predictions if global carbon emissions continued on their current trend.
"It clearly shows that we will lose the coldness of our winters, which in turn will affect our rainfall," he said.
"That will have an impact of our industries. Agriculture is a major industry in the Riverina, producing more than $900 million."
Dr Howard said the predicted temperature increases would have a profound impact Murrumbidgee River water flows and on Riverina towns that were dependent on farming.
The Australian Conservation Foundation has declared the Riverina one of the top ten federal electorates most at risk from climate change.
Foundation chief executive Kelly O’Shanassy too many MPs were failing their communities by failing to act on climate change.
“It is disappointing that many of the federal electorates found to have the highest projected increases in average maximum temperatures are represented by MPs who do little to champion climate action," she said.
Ms O’Shanassy called on Riverina MP Michael McCormack and New England MP Barnaby Joyce to do more to protect their electorates.
“(They) would do well to stop dismissing established climate science and get on with better representing their communities by championing pollution cuts and programs to help them adapt to changes already in the system," she said.
Mr McCormack said the federal government was getting the "right balance" between reducing emissions and protecting jobs and living costs.
“The Liberal and Nationals’ Government is taking positive and practical action on the environment and playing its part on the ground with a pragmatic policy approach," he said.
“We are doing this in a balanced and sensible way which acknowledges the practical experience of our farmers, who are the world’s best environmentalists.
“We are also doing this in a way which is sensible for the economy and local jobs, as well as power supply and affordability."
Labor Riverina candidate Mark Jeffreson said the foundation's study showed the need to transition to renewable energy.
"We're a region where a lot relies on the weather and the scientists have been telling us for a number of years that if we don't begin acting then our situation is going to get worse and worse," he said.
"We will see more an more extreme events, which we have probably begun to see already this season with bushfires in October that are still going in March.
"Being the most at risk from climate change is probably a 'top 10' that we don't want to be in."
Mr Jeffreson said current coal-fired power stations "have to be a part of the system" until they are replaced.
"Until we replace the systems that we have got, we are not completely ready for the new ones," he said.
Greens candidate Michael Bayles said the predicted consequences for the Riverina demanded the replacement of fossil fuels in transport and energy generation.
"I have noticed in Wagga the number of days that are high in temperature and the thunderstorms," he said.
"If you look at the Intergovernmental Panel on Climate Change, there is a small window to start acting."
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